Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Corticotropin-releasing factor receptor 1' and Ligand = 'BDBM50203603'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Corticotropin-releasing factor receptor 1 (Homo sapiens (Human))	BDBM50203603 (CHEMBL428044 | [8-(2-chloro-4,6-dimethyl-phenyl)-2...) Show SMILES CN(CCc1ccncc1)Cc1c(C)nc2n(-c3c(C)cc(C)cc3Cl)c3ncccc3n12 |(17.91,.48,;18.9,-.69,;20.42,-.43,;20.95,1.02,;19.96,2.2,;20.5,3.64,;19.51,4.82,;18,4.56,;17.47,3.1,;18.45,1.93,;18.38,-2.14,;19.37,-3.32,;19,-4.81,;17.58,-5.39,;20.31,-5.62,;21.49,-4.64,;23.03,-4.53,;24.02,-5.71,;25.52,-5.44,;26.05,-3.99,;26.51,-6.61,;25.99,-8.07,;26.98,-9.25,;24.47,-8.33,;23.48,-7.15,;21.97,-7.42,;23.4,-3.04,;24.77,-2.32,;24.83,-.77,;23.45,.12,;22.15,-.67,;22.09,-2.21,;20.91,-3.2,)| Show InChI InChI=1S/C26H27ClN6/c1-17-14-18(2)24(21(27)15-17)33-25-22(6-5-10-29-25)32-23(19(3)30-26(32)33)16-31(4)13-9-20-7-11-28-12-8-20/h5-8,10-12,14-15H,9,13,16H2,1-4H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	3.20E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Displacement of [125I]Tyr-o-CRF from CRF1 receptor expressed in IMR32 cells assessed as inhibition of CRF stimulated cAMP production				Bioorg Med Chem Lett 17: 2026-30 (2007) Article DOI: 10.1016/j.bmcl.2007.01.008 BindingDB Entry DOI: 10.7270/Q21R6Q5Q
					More data for this Ligand-Target Pair