Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Corticotropin-releasing factor receptor 1' and Ligand = 'BDBM50203627'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Corticotropin-releasing factor receptor 1 (Homo sapiens (Human))	BDBM50203627 (CHEMBL392044 | [8-(2-chloro-4,6-dimethyl-phenyl)-2...) Show SMILES CN(Cc1c(C)nc2n(-c3c(C)cc(C)cc3Cl)c3ncccc3n12)Cc1ccncc1 |(4.83,-35.64,;5.82,-36.8,;5.3,-38.25,;6.29,-39.43,;5.92,-40.92,;4.49,-41.5,;7.23,-41.74,;8.41,-40.75,;9.95,-40.64,;10.94,-41.82,;12.44,-41.55,;12.96,-40.1,;13.43,-42.73,;12.91,-44.18,;13.9,-45.36,;11.39,-44.45,;10.4,-43.27,;8.88,-43.53,;10.32,-39.15,;11.69,-38.43,;11.75,-36.88,;10.37,-35.99,;9.06,-36.79,;9.01,-38.33,;7.83,-39.32,;7.34,-36.54,;7.87,-35.1,;9.39,-34.84,;9.92,-33.4,;8.93,-32.21,;7.41,-32.48,;6.88,-33.93,)| Show InChI InChI=1S/C25H25ClN6/c1-16-12-17(2)23(20(26)13-16)32-24-21(6-5-9-28-24)31-22(18(3)29-25(31)32)15-30(4)14-19-7-10-27-11-8-19/h5-13H,14-15H2,1-4H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	1.20E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Displacement of [125I]Tyr-o-CRF from CRF1 receptor expressed in IMR32 cells assessed as inhibition of CRF stimulated cAMP production				Bioorg Med Chem Lett 17: 2026-30 (2007) Article DOI: 10.1016/j.bmcl.2007.01.008 BindingDB Entry DOI: 10.7270/Q21R6Q5Q
					More data for this Ligand-Target Pair