Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Corticotropin-releasing factor receptor 1' and Ligand = 'BDBM50300140'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Corticotropin-releasing factor receptor 1 (Rattus norvegicus (rat))	BDBM50300140 ((R)-4-(1-Cyclopropylpropyl)-6-(6-methoxy-2,5-dimet...) Show SMILES CC[C@H](C1CC1)n1cc(nc(Nc2cc(C)c(OC)nc2C)c1=O)C#N |r| Show InChI InChI=1S/C19H23N5O2/c1-5-16(13-6-7-13)24-10-14(9-20)22-17(19(24)25)23-15-8-11(2)18(26-4)21-12(15)3/h8,10,13,16H,5-7H2,1-4H3,(H,22,23)/t16-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.70	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company Curated by ChEMBL					Assay Description Displacement of [125I]Tyr-o-CRF from CRF1 receptor in rat frontal cortex homogenate by binding titration assay				J Med Chem 52: 7653-68 (2009) Article DOI: 10.1021/jm900716v BindingDB Entry DOI: 10.7270/Q2CN740W
					More data for this Ligand-Target Pair