Compile Data Set for Download or QSAR

Found 3 hits Enz. Inhib. hit(s) with Target = 'Corticotropin-releasing factor receptor 1' and Ligand = 'BDBM50302593'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Corticotropin-releasing factor receptor 1 (Homo sapiens (Human))	BDBM50302593 (1-(4-methoxy-2-methylphenyl)-N-(2-methoxyethyl)-3,...) Show SMILES CCCN(CCOC)c1nc(C)nc2n(nc(C)c12)-c1ccc(OC)cc1C Show InChI InChI=1S/C21H29N5O2/c1-7-10-25(11-12-27-5)20-19-15(3)24-26(21(19)23-16(4)22-20)18-9-8-17(28-6)13-14(18)2/h8-9,13H,7,10-12H2,1-6H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	13	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Antagonist activity at human recombinant CRF1 receptor expressed in CHO cells assessed as inhibition of CRF-induced cAMP production				Bioorg Med Chem Lett 19: 6144-7 (2009) Article DOI: 10.1016/j.bmcl.2009.09.016 BindingDB Entry DOI: 10.7270/Q2FT8M46
					More data for this Ligand-Target Pair
Corticotropin-releasing factor receptor 1 (Homo sapiens (Human))	BDBM50302593 (1-(4-methoxy-2-methylphenyl)-N-(2-methoxyethyl)-3,...) Show SMILES CCCN(CCOC)c1nc(C)nc2n(nc(C)c12)-c1ccc(OC)cc1C Show InChI InChI=1S/C21H29N5O2/c1-7-10-25(11-12-27-5)20-19-15(3)24-26(21(19)23-16(4)22-20)18-9-8-17(28-6)13-14(18)2/h8-9,13H,7,10-12H2,1-6H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	13	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Antagonist activity at recombinant human CRF1 receptor expressed in CHO cells assessed as inhibition of CRF-induced cAMP formation				Bioorg Med Chem Lett 21: 6108-11 (2011) Article DOI: 10.1016/j.bmcl.2011.08.040 BindingDB Entry DOI: 10.7270/Q2F19046
					More data for this Ligand-Target Pair
Corticotropin-releasing factor receptor 1 (Homo sapiens (Human))	BDBM50302593 (1-(4-methoxy-2-methylphenyl)-N-(2-methoxyethyl)-3,...) Show SMILES CCCN(CCOC)c1nc(C)nc2n(nc(C)c12)-c1ccc(OC)cc1C Show InChI InChI=1S/C21H29N5O2/c1-7-10-25(11-12-27-5)20-19-15(3)24-26(21(19)23-16(4)22-20)18-9-8-17(28-6)13-14(18)2/h8-9,13H,7,10-12H2,1-6H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	14	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Binding affinity to recombinant human CRF1 receptor expressed in CHO cells				Bioorg Med Chem Lett 21: 6108-11 (2011) Article DOI: 10.1016/j.bmcl.2011.08.040 BindingDB Entry DOI: 10.7270/Q2F19046
					More data for this Ligand-Target Pair