Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Corticotropin-releasing factor receptor 1' and Ligand = 'BDBM50351383'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Corticotropin-releasing factor receptor 1 (Homo sapiens (Human))	BDBM50351383 (CHEMBL1819073) Show SMILES CCC(CC)Nc1c2CCCc2nc2c(c(C)nn12)-c1ccc(cc1C)N(C)C |(26.44,3.99,;25.09,3.25,;25.07,1.71,;26.38,.91,;27.73,1.66,;23.72,.96,;23.69,-.58,;22.34,-1.32,;20.88,-.82,;19.95,-2.05,;20.83,-3.31,;22.31,-2.86,;23.63,-3.66,;24.99,-2.9,;26.44,-3.39,;27.36,-2.16,;28.9,-2.18,;26.47,-.91,;25.01,-1.37,;26.9,-4.86,;25.86,-5.99,;26.31,-7.46,;27.82,-7.8,;28.86,-6.66,;28.4,-5.2,;29.44,-4.06,;28.28,-9.27,;27.24,-10.4,;29.78,-9.61,)| Show InChI InChI=1S/C24H33N5/c1-7-17(8-2)25-23-20-10-9-11-21(20)26-24-22(16(4)27-29(23)24)19-13-12-18(28(5)6)14-15(19)3/h12-14,17,25H,7-11H2,1-6H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	38	n/a	n/a	n/a	n/a	n/a	n/a
Minase Research Institute Curated by ChEMBL					Assay Description Displacement of [125I]CRF from human corticotropin-releasing factor receptor 1 expressed in CHO-K1 cells after 2 hrs by gamma counting				Bioorg Med Chem 19: 5432-45 (2011) Article DOI: 10.1016/j.bmc.2011.07.055 BindingDB Entry DOI: 10.7270/Q2Z038JX
					More data for this Ligand-Target Pair