Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Corticotropin-releasing factor receptor 1' and Ligand = 'BDBM50351398'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Corticotropin-releasing factor receptor 1 (Homo sapiens (Human))	BDBM50351398 (CHEMBL1819088) Show SMILES CCC(CC)Nc1c2CCOc2nc2c(c(C)nn12)-c1ccc(OC)cc1Cl |(15.19,-12.03,;13.84,-12.77,;13.81,-14.31,;15.13,-15.11,;16.48,-14.36,;12.46,-15.06,;12.43,-16.6,;11.08,-17.34,;9.62,-16.84,;8.69,-18.07,;9.58,-19.33,;11.05,-18.89,;12.38,-19.74,;13.73,-18.92,;15.19,-19.42,;16.11,-18.18,;17.65,-18.2,;15.22,-16.93,;13.75,-17.39,;15.65,-20.89,;14.6,-22.02,;15.06,-23.48,;16.56,-23.82,;17.02,-25.29,;15.98,-26.43,;17.61,-22.68,;17.15,-21.22,;18.19,-20.08,)| Show InChI InChI=1S/C21H25ClN4O2/c1-5-13(6-2)23-19-16-9-10-28-21(16)24-20-18(12(3)25-26(19)20)15-8-7-14(27-4)11-17(15)22/h7-8,11,13,23H,5-6,9-10H2,1-4H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	84	n/a	n/a	n/a	n/a	n/a	n/a
Minase Research Institute Curated by ChEMBL					Assay Description Displacement of [125I]CRF from human corticotropin-releasing factor receptor 1 expressed in CHO-K1 cells after 2 hrs by gamma counting				Bioorg Med Chem 19: 5432-45 (2011) Article DOI: 10.1016/j.bmc.2011.07.055 BindingDB Entry DOI: 10.7270/Q2Z038JX
					More data for this Ligand-Target Pair
Corticotropin-releasing factor receptor 1 (Homo sapiens (Human))	BDBM50351398 (CHEMBL1819088) Show SMILES CCC(CC)Nc1c2CCOc2nc2c(c(C)nn12)-c1ccc(OC)cc1Cl |(15.19,-12.03,;13.84,-12.77,;13.81,-14.31,;15.13,-15.11,;16.48,-14.36,;12.46,-15.06,;12.43,-16.6,;11.08,-17.34,;9.62,-16.84,;8.69,-18.07,;9.58,-19.33,;11.05,-18.89,;12.38,-19.74,;13.73,-18.92,;15.19,-19.42,;16.11,-18.18,;17.65,-18.2,;15.22,-16.93,;13.75,-17.39,;15.65,-20.89,;14.6,-22.02,;15.06,-23.48,;16.56,-23.82,;17.02,-25.29,;15.98,-26.43,;17.61,-22.68,;17.15,-21.22,;18.19,-20.08,)| Show InChI InChI=1S/C21H25ClN4O2/c1-5-13(6-2)23-19-16-9-10-28-21(16)24-20-18(12(3)25-26(19)20)15-8-7-14(27-4)11-17(15)22/h7-8,11,13,23H,5-6,9-10H2,1-4H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	8	n/a	n/a	n/a	n/a
Minase Research Institute Curated by ChEMBL					Assay Description Antagonist activity at human corticotropin-releasing factor receptor 1 expressed in CHO-K1 cells assessed as inhibition of CRF-induced cAMP productio...				Bioorg Med Chem 19: 5432-45 (2011) Article DOI: 10.1016/j.bmc.2011.07.055 BindingDB Entry DOI: 10.7270/Q2Z038JX
					More data for this Ligand-Target Pair