Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Corticotropin-releasing factor receptor 1' and Ligand = 'BDBM50417501'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Corticotropin-releasing factor receptor 1 (Homo sapiens (Human))	BDBM50417501 (CHEMBL1287904) Show SMILES CCC(Nc1cc(C)nc2c(c(C)nn12)-c1ccc(OC)cc1C)c1nc(C)no1 |(-2.06,-31.7,;-3.39,-32.46,;-3.39,-34,;-2.06,-34.77,;-2.07,-36.31,;-3.41,-37.08,;-3.41,-38.62,;-4.75,-39.39,;-2.08,-39.39,;-.75,-38.62,;.72,-39.1,;1.63,-37.87,;3.17,-37.87,;.72,-36.62,;-.74,-37.08,;1.47,-40.45,;.69,-41.78,;1.43,-43.1,;2.97,-43.13,;3.72,-44.47,;5.27,-44.5,;3.76,-41.82,;3.01,-40.46,;3.8,-39.14,;-4.65,-34.89,;-6.11,-34.39,;-7.02,-35.61,;-8.56,-35.59,;-6.14,-36.88,;-4.66,-36.43,)| Show InChI InChI=1S/C22H26N6O2/c1-7-18(22-24-15(5)27-30-22)25-19-11-13(3)23-21-20(14(4)26-28(19)21)17-9-8-16(29-6)10-12(17)2/h8-11,18,25H,7H2,1-6H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	7.94	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences Curated by ChEMBL					Assay Description Antagonist activity at human recombinant CRF1 receptor				Bioorg Med Chem Lett 20: 7259-64 (2010) Article DOI: 10.1016/j.bmcl.2010.10.095 BindingDB Entry DOI: 10.7270/Q2736S5V
					More data for this Ligand-Target Pair