Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Corticotropin-releasing factor receptor 1' and Ligand = 'BDBM50417504'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Corticotropin-releasing factor receptor 1 (Homo sapiens (Human))	BDBM50417504 (CHEMBL1287936) Show SMILES COc1ccc(-c2c(C)nn3c(NC4(CC4)c4nc(C)no4)cc(C)nc23)c(C)c1 |(27.22,-34.82,;25.68,-34.81,;24.91,-33.47,;23.37,-33.46,;22.62,-32.15,;23.39,-30.81,;22.62,-29.48,;23.52,-28.23,;25.06,-28.22,;22.6,-26.99,;21.15,-27.47,;19.81,-26.71,;19.8,-25.17,;18.45,-24.41,;17.68,-23.07,;19.22,-23.07,;17.21,-25.32,;15.75,-24.84,;14.85,-26.06,;13.31,-26.06,;15.74,-27.32,;17.22,-26.86,;18.47,-27.49,;18.49,-29.03,;17.16,-29.81,;19.83,-29.79,;21.15,-29.01,;24.92,-30.81,;25.7,-29.48,;25.69,-32.16,)| Show InChI InChI=1S/C22H24N6O2/c1-12-10-16(29-5)6-7-17(12)19-14(3)26-28-18(11-13(2)23-20(19)28)25-22(8-9-22)21-24-15(4)27-30-21/h6-7,10-11,25H,8-9H2,1-5H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	31.6	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences Curated by ChEMBL					Assay Description Antagonist activity at human recombinant CRF1 receptor				Bioorg Med Chem Lett 20: 7259-64 (2010) Article DOI: 10.1016/j.bmcl.2010.10.095 BindingDB Entry DOI: 10.7270/Q2736S5V
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