Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Corticotropin-releasing factor receptor 1' and Ligand = 'BDBM50420919'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Corticotropin-releasing factor receptor 1 (Homo sapiens (Human))	BDBM50420919 (CHEMBL2087566) Show SMILES CCc1nn2c(cccc2c1N(CC1CC1)CC1CCOCC1)-c1c(OC)cc(CO)cc1OC |(-4.48,1.82,;-3.71,.48,;-2.17,.49,;-1.26,-.76,;.2,-.28,;1.54,-1.05,;2.87,-.28,;2.87,1.26,;1.53,2.03,;.2,1.26,;-1.27,1.73,;-1.74,3.2,;-.71,4.34,;.81,4.1,;2.24,4.66,;2,3.14,;-3.25,3.52,;-3.65,5,;-5.14,5.4,;-5.54,6.89,;-4.45,7.98,;-2.96,7.58,;-2.56,6.09,;1.54,-2.59,;.2,-3.36,;-1.13,-2.59,;-2.46,-3.36,;.21,-4.9,;1.54,-5.67,;1.54,-7.21,;2.88,-7.98,;2.87,-4.9,;2.87,-3.36,;4.2,-2.59,;5.54,-3.35,)| Show InChI InChI=1S/C28H37N3O4/c1-4-22-28(30(16-19-8-9-19)17-20-10-12-35-13-11-20)24-7-5-6-23(31(24)29-22)27-25(33-2)14-21(18-32)15-26(27)34-3/h5-7,14-15,19-20,32H,4,8-13,16-18H2,1-3H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	200	n/a	n/a	n/a	n/a	n/a	n/a
Eisai Co., Ltd. Curated by ChEMBL					Assay Description Displacement of [125I]CRF from human CRF1 receptor expressed in HEK293 cells after 2 hrs by liquid scintillation counter				J Med Chem 55: 5255-69 (2012) Article DOI: 10.1021/jm300259r BindingDB Entry DOI: 10.7270/Q29P32XC
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