Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Corticotropin-releasing factor receptor 1' and Ligand = 'BDBM50420923'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Corticotropin-releasing factor receptor 1 (Homo sapiens (Human))	BDBM50420923 (CHEMBL2087570) Show SMILES CCc1nn2c(cccc2c1N(CC1CC1)CC1CCOCC1)-c1c(OC)cccc1OC |(-4.48,.73,;-3.74,-.62,;-2.2,-.65,;-1.32,-1.92,;.15,-1.47,;1.47,-2.27,;2.82,-1.53,;2.85,.01,;1.54,.81,;.19,.07,;-1.27,.57,;-1.71,2.05,;-.65,3.17,;.86,2.9,;2.31,3.42,;2.04,1.9,;-3.21,2.4,;-3.57,3.9,;-5.05,4.33,;-5.42,5.83,;-4.3,6.89,;-2.83,6.46,;-2.46,4.96,;1.43,-3.81,;2.75,-4.61,;4.1,-3.87,;5.42,-4.67,;2.72,-6.15,;1.36,-6.89,;.05,-6.09,;.08,-4.55,;-1.23,-3.75,;-2.58,-4.49,)| Show InChI InChI=1S/C27H35N3O3/c1-4-21-27(29(17-19-11-12-19)18-20-13-15-33-16-14-20)23-8-5-7-22(30(23)28-21)26-24(31-2)9-6-10-25(26)32-3/h5-10,19-20H,4,11-18H2,1-3H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	105	n/a	n/a	n/a	n/a	n/a	n/a
Eisai Co., Ltd. Curated by ChEMBL					Assay Description Displacement of [125I]CRF from human CRF1 receptor expressed in HEK293 cells after 2 hrs by liquid scintillation counter				J Med Chem 55: 5255-69 (2012) Article DOI: 10.1021/jm300259r BindingDB Entry DOI: 10.7270/Q29P32XC
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