Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Corticotropin-releasing factor receptor 1' and Ligand = 'BDBM50420927'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Corticotropin-releasing factor receptor 1 (Homo sapiens (Human))	BDBM50420927 (CHEMBL2087574) Show SMILES COCc1cc(OC)c(c(OC)c1)-c1cccc2c(N(CC3CC3)CC3CCOCC3)c(SC)nn12 |(2.74,-8.79,;2.75,-7.25,;1.43,-6.47,;1.45,-4.93,;2.79,-4.17,;2.81,-2.63,;4.15,-1.88,;5.47,-2.66,;1.48,-1.85,;.14,-2.6,;-1.18,-1.82,;-2.53,-2.57,;.12,-4.14,;1.5,-.31,;2.84,.45,;2.86,1.99,;1.53,2.77,;.19,2.02,;-1.27,2.51,;-1.73,3.98,;-.68,5.11,;.84,4.85,;2.28,5.39,;2.02,3.87,;-3.23,4.32,;-3.61,5.81,;-5.09,6.22,;-5.47,7.72,;-4.37,8.79,;-2.89,8.38,;-2.51,6.89,;-2.19,1.27,;-3.73,1.29,;-4.48,2.63,;-1.29,.02,;.18,.48,)| Show InChI InChI=1S/C28H37N3O4S/c1-32-18-21-14-24(33-2)26(25(15-21)34-3)22-6-5-7-23-27(28(36-4)29-31(22)23)30(16-19-8-9-19)17-20-10-12-35-13-11-20/h5-7,14-15,19-20H,8-13,16-18H2,1-4H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	30	n/a	n/a	n/a	n/a	n/a	n/a
Eisai Co., Ltd. Curated by ChEMBL					Assay Description Antagonist activity at human CRF1 receptor expressed in HEK293 cells assessed as inhibition of CRF-stimulated cAMP accumulation after 30 mins by fluo...				J Med Chem 55: 5255-69 (2012) Article DOI: 10.1021/jm300259r BindingDB Entry DOI: 10.7270/Q29P32XC
					More data for this Ligand-Target Pair
Corticotropin-releasing factor receptor 1 (Homo sapiens (Human))	BDBM50420927 (CHEMBL2087574) Show SMILES COCc1cc(OC)c(c(OC)c1)-c1cccc2c(N(CC3CC3)CC3CCOCC3)c(SC)nn12 |(2.74,-8.79,;2.75,-7.25,;1.43,-6.47,;1.45,-4.93,;2.79,-4.17,;2.81,-2.63,;4.15,-1.88,;5.47,-2.66,;1.48,-1.85,;.14,-2.6,;-1.18,-1.82,;-2.53,-2.57,;.12,-4.14,;1.5,-.31,;2.84,.45,;2.86,1.99,;1.53,2.77,;.19,2.02,;-1.27,2.51,;-1.73,3.98,;-.68,5.11,;.84,4.85,;2.28,5.39,;2.02,3.87,;-3.23,4.32,;-3.61,5.81,;-5.09,6.22,;-5.47,7.72,;-4.37,8.79,;-2.89,8.38,;-2.51,6.89,;-2.19,1.27,;-3.73,1.29,;-4.48,2.63,;-1.29,.02,;.18,.48,)| Show InChI InChI=1S/C28H37N3O4S/c1-32-18-21-14-24(33-2)26(25(15-21)34-3)22-6-5-7-23-27(28(36-4)29-31(22)23)30(16-19-8-9-19)17-20-10-12-35-13-11-20/h5-7,14-15,19-20H,8-13,16-18H2,1-4H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	35	n/a	n/a	n/a	n/a	n/a	n/a
Eisai Co., Ltd. Curated by ChEMBL					Assay Description Displacement of [125I]CRF from human CRF1 receptor expressed in HEK293 cells after 2 hrs by liquid scintillation counter				J Med Chem 55: 5255-69 (2012) Article DOI: 10.1021/jm300259r BindingDB Entry DOI: 10.7270/Q29P32XC
					More data for this Ligand-Target Pair