Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Corticotropin-releasing factor receptor 1' and Ligand = 'BDBM50420937'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Corticotropin-releasing factor receptor 1 (Homo sapiens (Human))	BDBM50420937 (CHEMBL2087801) Show SMILES COCCN(CC1CCOCC1)c1c(SC)nn2c(cccc12)-c1c(OC)cc(COC)cc1OC |(-3.55,8.8,;-3.16,7.31,;-4.26,6.23,;-3.88,4.74,;-2.37,4.4,;-1.02,5.88,;.5,5.63,;1.04,4.18,;2.56,3.93,;3.54,5.12,;3,6.56,;1.48,6.81,;-1.77,2.49,;-2.69,1.26,;-4.23,1.27,;-4.99,2.61,;-1.79,0,;-.32,.47,;1,-.32,;2.34,.44,;2.36,1.98,;1.03,2.76,;-.31,2.01,;.99,-1.86,;2.32,-2.64,;3.66,-1.88,;4.99,-2.66,;2.3,-4.18,;.96,-4.94,;.95,-6.48,;2.28,-7.26,;2.27,-8.8,;-.36,-4.15,;-.35,-2.61,;-1.68,-1.83,;-3.02,-2.59,)| Show InChI InChI=1S/C27H37N3O5S/c1-31-14-11-29(17-19-9-12-35-13-10-19)26-22-8-6-7-21(30(22)28-27(26)36-5)25-23(33-3)15-20(18-32-2)16-24(25)34-4/h6-8,15-16,19H,9-14,17-18H2,1-5H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	34	n/a	n/a	n/a	n/a	n/a	n/a
Eisai Co., Ltd. Curated by ChEMBL					Assay Description Displacement of [125I]CRF from human CRF1 receptor expressed in HEK293 cells after 2 hrs by liquid scintillation counter				J Med Chem 55: 5255-69 (2012) Article DOI: 10.1021/jm300259r BindingDB Entry DOI: 10.7270/Q29P32XC
					More data for this Ligand-Target Pair
Corticotropin-releasing factor receptor 1 (Homo sapiens (Human))	BDBM50420937 (CHEMBL2087801) Show SMILES COCCN(CC1CCOCC1)c1c(SC)nn2c(cccc12)-c1c(OC)cc(COC)cc1OC |(-3.55,8.8,;-3.16,7.31,;-4.26,6.23,;-3.88,4.74,;-2.37,4.4,;-1.02,5.88,;.5,5.63,;1.04,4.18,;2.56,3.93,;3.54,5.12,;3,6.56,;1.48,6.81,;-1.77,2.49,;-2.69,1.26,;-4.23,1.27,;-4.99,2.61,;-1.79,0,;-.32,.47,;1,-.32,;2.34,.44,;2.36,1.98,;1.03,2.76,;-.31,2.01,;.99,-1.86,;2.32,-2.64,;3.66,-1.88,;4.99,-2.66,;2.3,-4.18,;.96,-4.94,;.95,-6.48,;2.28,-7.26,;2.27,-8.8,;-.36,-4.15,;-.35,-2.61,;-1.68,-1.83,;-3.02,-2.59,)| Show InChI InChI=1S/C27H37N3O5S/c1-31-14-11-29(17-19-9-12-35-13-10-19)26-22-8-6-7-21(30(22)28-27(26)36-5)25-23(33-3)15-20(18-32-2)16-24(25)34-4/h6-8,15-16,19H,9-14,17-18H2,1-5H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	124	n/a	n/a	n/a	n/a	n/a	n/a
Eisai Co., Ltd. Curated by ChEMBL					Assay Description Antagonist activity at human CRF1 receptor expressed in HEK293 cells assessed as inhibition of CRF-stimulated cAMP accumulation after 30 mins by fluo...				J Med Chem 55: 5255-69 (2012) Article DOI: 10.1021/jm300259r BindingDB Entry DOI: 10.7270/Q29P32XC
					More data for this Ligand-Target Pair