BindingDB logo
myBDB logout
Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Corticotropin-releasing factor receptor 1' and Ligand = 'BDBM50536893'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Corticotropin-releasing factor receptor 1


(Homo sapiens (Human))		BDBM50536893
PNG
(CHEMBL4527586)
Show SMILES COc1cc(Cl)cc(C)c1Nc1nc2cccc(N(C(C)C)c3ccc(C)cn3)c2n1C
Show InChI InChI=1S/C25H28ClN5O/c1-15(2)31(22-11-10-16(3)14-27-22)20-9-7-8-19-24(20)30(5)25(28-19)29-23-17(4)12-18(26)13-21(23)32-6/h7-15H,1-6H3,(H,28,29)
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 69n/an/an/an/an/an/a



Takeda Pharmaceutical Company Ltd

Curated by ChEMBL


Assay Description
Displacement of ovine [125I-Tyr0]-CRF from human CRF1 receptor expressed in CHO cell membrane measured after 1.5 hrs by TopCount method

Bioorg Med Chem 24: 4675-4691 (2016)


Article DOI: 10.1016/j.bmc.2016.08.005
BindingDB Entry DOI: 10.7270/Q2G164BQ
More data for this
Ligand-Target Pair