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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Corticotropin-releasing factor receptor 1' and Ligand = 'BDBM50536896'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Corticotropin-releasing factor receptor 1


(Homo sapiens (Human))		BDBM50536896
PNG
(CHEMBL4526083)
Show SMILES COc1cc(Br)cc(C)c1Nc1nc2cccc(N(C(C)C)c3cccc(c3)C(C)(C)C(N)=O)c2n1C
Show InChI InChI=1S/C29H34BrN5O2/c1-17(2)35(21-11-8-10-19(15-21)29(4,5)27(31)36)23-13-9-12-22-26(23)34(6)28(32-22)33-25-18(3)14-20(30)16-24(25)37-7/h8-17H,1-7H3,(H2,31,36)(H,32,33)
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Article
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n/an/a 120n/an/an/an/an/an/a



Takeda Pharmaceutical Company Ltd

Curated by ChEMBL


Assay Description
Displacement of ovine [125I-Tyr0]-CRF from human CRF1 receptor expressed in CHO cell membrane measured after 1.5 hrs by TopCount method

Bioorg Med Chem 24: 4675-4691 (2016)


Article DOI: 10.1016/j.bmc.2016.08.005
BindingDB Entry DOI: 10.7270/Q2G164BQ
More data for this
Ligand-Target Pair