Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Corticotropin-releasing factor receptor 2' and Ligand = 'BDBM131860'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Corticotropin-releasing factor receptor 2 (Homo sapiens (Human))	BDBM131860 (US8835444, 1.8) Show SMILES COc1ccc(-c2c(C)[nH]nc2NC[C@H]2CC[C@@H](CC2)NC(=O)c2cc(ccc2Cl)C(F)(F)F)c(Cl)c1 |r,wU:14.14,wD:17.21,(5.96,-4.65,;7.29,-3.88,;7.29,-2.34,;5.96,-1.57,;5.96,-.03,;7.29,.74,;7.29,2.28,;8.54,3.19,;9.87,2.42,;8.06,4.65,;6.52,4.65,;6.05,3.19,;4.71,2.42,;3.38,3.19,;2.04,2.42,;2.04,.88,;.71,.11,;-.62,.88,;-.62,2.42,;.71,3.19,;-1.96,.11,;-3.29,.88,;-3.29,2.42,;-4.62,.11,;-5.96,.88,;-7.29,.11,;-7.29,-1.43,;-5.96,-2.2,;-4.62,-1.43,;-3.29,-2.2,;-8.62,.88,;-9.96,.11,;-8.62,2.42,;-7.29,1.65,;8.62,-.03,;9.96,.74,;8.62,-1.57,)| Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	727	n/a	n/a	n/a	n/a	n/a	n/a
Novartis AG US Patent					Assay Description Chinese hamster ovary (CHO) cells expressing either the human or rat recombinant CRF-1 or human CRF-2alpha (Chen et al, Proc Natl Acad Sci USA 90, 89...				US Patent US8835444 (2014) BindingDB Entry DOI: 10.7270/Q28K77ST
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