Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Cyclic AMP-dependent transcription factor ATF-1' and Ligand = 'BDBM50062671'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cyclic AMP-dependent transcription factor ATF-1 (Homo sapiens (Human))	BDBM50062671 (3-[(2-Chloro-4-trifluoromethyl-pyrimidine-5-carbon...) Show SMILES CCOP(=O)(COC(=O)c1cc(NC(=O)c2cnc(Cl)nc2C(F)(F)F)cc(c1)C(F)(F)F)OCC Show InChI InChI=1S/C19H17ClF6N3O6P/c1-3-34-36(32,35-4-2)9-33-16(31)10-5-11(18(21,22)23)7-12(6-10)28-15(30)13-8-27-17(20)29-14(13)19(24,25)26/h5-8H,3-4,9H2,1-2H3,(H,28,30)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Signal Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description In vitro inhibitory activity against human Jurkat T-Cells stably transfected with activating transcription factor 1				J Med Chem 41: 413-9 (1998) Article DOI: 10.1021/jm970671g BindingDB Entry DOI: 10.7270/Q2P55MMZ
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