Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Cyclin-A2 [177-432]/Cyclin-dependent kinase 2' and Ligand = 'BDBM515905'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cyclin-A2 [177-432]/Cyclin-dependent kinase 2 (Homo sapiens (Human))	BDBM515905 (N-(5-((4-ethylpiperazin- 1-yl)methyl) pyridin-2-yl...) Show SMILES CCN1CCN(Cc2ccc(Nc3ncc(F)c(n3)-c3cc(F)c4nc5CCCC(C)n5c4c3)nc2)CC1 Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	>300	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description To demonstrate that the compounds exhibit affinity for CDK kinases (CDK2/CycA2, CDK4/CycD3, CDK6/cycD3), CDK kinase assays were performed.Reaction bu...				Citation and Details BindingDB Entry DOI: 10.7270/Q2959MRV
					More data for this Ligand-Target Pair