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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Cyclin-C/Cyclin-dependent kinase 8' and Ligand = 'BDBM350250'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Cyclin-C/Cyclin-dependent kinase 8


(Homo sapiens (Human))		BDBM350250
PNG
(US10208056, Compound 77)
Show SMILES CC(=O)N1CCC2(CC1)Oc1cnccc1-c1[nH]c(cc21)C(N)=O
Show InChI InChI=1S/C17H18N4O3/c1-10(22)21-6-3-17(4-7-21)12-8-13(16(18)23)20-15(12)11-2-5-19-9-14(11)24-17/h2,5,8-9,20H,3-4,6-7H2,1H3,(H2,18,23)
PDB

KEGG

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 7.48n/an/an/an/an/an/a



FUNDACIÓN DEL SECTOR PÚBLICO ESTATAL CENTRO NACIONAL DE INVESTIGACIONES ONCOLÓGICAS CARLOS III (F.S.P. CNIO)

US Patent


Assay Description
The binding assay relies on the LanthaScreen™ Eu-Kinase Binding Assay (Invitrogen. This is a kinase assay platform based on measuring the binding and...

US Patent US10208056 (2019)


BindingDB Entry DOI: 10.7270/Q2GB266B
More data for this
Ligand-Target Pair