Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Cyclin-T1' and Ligand = 'BDBM126509'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cyclin-T1 (Homo sapiens (Human))	BDBM126509 (US8778951, 320) Show SMILES CC1(C)OC[C@@H](CN[C@H]2CC[C@@H](CC2)Nc2cc(c(Cl)cn2)-c2nc(NCC3CCOCC3)ccc2Cl)O1 |r,wU:11.14,5.5,wD:8.7,(8.24,1.68,;6.91,.91,;8.24,.14,;6,-.34,;4.54,.14,;4.54,1.68,;3.21,2.45,;1.87,1.68,;.54,2.45,;.54,3.99,;-.79,4.76,;-2.13,3.99,;-2.13,2.45,;-.79,1.68,;-3.46,4.76,;-4.8,3.99,;-4.8,2.45,;-6.13,1.68,;-7.46,2.45,;-8.8,1.68,;-7.46,3.99,;-6.13,4.76,;-6.13,.14,;-4.8,-.63,;-4.8,-2.17,;-3.46,-2.94,;-2.13,-2.17,;-.79,-2.94,;-.79,-4.48,;.54,-5.25,;1.87,-4.48,;1.87,-2.94,;.54,-2.17,;-6.13,-2.94,;-7.46,-2.17,;-7.46,-.63,;-8.8,.14,;6,2.15,)| Show InChI InChI=1S/C28H39Cl2N5O3/c1-28(2)37-17-21(38-28)15-31-19-3-5-20(6-4-19)34-26-13-22(24(30)16-33-26)27-23(29)7-8-25(35-27)32-14-18-9-11-36-12-10-18/h7-8,13,16,18-21,31H,3-6,9-12,14-15,17H2,1-2H3,(H,32,35)(H,33,34)/t19-,20-,21-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	0.00100	n/a	n/a	n/a	n/a	n/a	n/a
Novartis AG US Patent					Assay Description Cdk9/cyclinT1 is purchased from Millipore, cat #14-685. The final total protein concentration in the assay 4 nM. The 5TAMRA-cdk7tide peptide substrat...				US Patent US8778951 (2014) BindingDB Entry DOI: 10.7270/Q25B014T
					More data for this Ligand-Target Pair