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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Cyclin-dependent kinase 1/G2/mitotic-specific cyclin-B' and Ligand = 'BDBM5480'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Cyclin-dependent kinase 1/G2/mitotic-specific cyclin-B


(Marthasterias glacialis (starfish))		BDBM5480
PNG
(2-Amino-6-(2 -cyclohexylidenethoxy)]purine | 6-(2-...)
Show SMILES Nc1nc(OCC=C2CCCCC2)c2[nH]cnc2n1 |(-4.42,.15,;-3.08,.92,;-3.08,2.46,;-1.75,3.23,;-1.73,4.77,;-3.07,5.54,;-4.4,4.77,;-5.74,5.54,;-5.71,7.08,;-7.03,7.87,;-8.38,7.12,;-8.4,5.58,;-7.08,4.79,;-.47,2.46,;.99,2.94,;1.9,1.69,;.99,.45,;-.47,.92,;-1.75,.15,)|
Show InChI InChI=1S/C13H17N5O/c14-13-17-11-10(15-8-16-11)12(18-13)19-7-6-9-4-2-1-3-5-9/h6,8H,1-5,7H2,(H3,14,15,16,17,18)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/an/an/an/an/an/an/an/a



University of Newcastle



Assay Description
The enzyme was assayed with substrate histone H1 in the presence of 12.5 uM ATP/[gamma-32P] ATP. IC50 is the inhibitor concentration, which inhibits ...

J Med Chem 45: 3381-93 (2002)


Article DOI: 10.1021/jm020056z
BindingDB Entry DOI: 10.7270/Q2891424
More data for this
Ligand-Target Pair