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Found 1 hit Enz. Inhib. hit(s) with Target = 'Cyclin-dependent kinase 2/G1/S-specific cyclin-E1' and Ligand = 'BDBM50134090'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Cyclin-dependent kinase 2/G1/S-specific cyclin-E1


(Homo sapiens (Human))		BDBM50134090
PNG
(CHEMBL3735561)
Show SMILES COCC(=O)Nc1cccc(Nc2ncc(F)c(Nc3ccc(F)cc3)n2)c1
Show InChI InChI=1S/C19H17F2N5O2/c1-28-11-17(27)23-14-3-2-4-15(9-14)25-19-22-10-16(21)18(26-19)24-13-7-5-12(20)6-8-13/h2-10H,11H2,1H3,(H,23,27)(H2,22,24,25,26)
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Similars
PubMed
n/an/a 3.27E+3n/an/an/an/an/an/a



Chinese Academy of Medical Sciences and Peking Union Medical College

Curated by ChEMBL


Assay Description
Inhibition of CDK2/cyclin E1 (unknown origin) expressed in Sf9 insect cells using UlightCFFKNIVTPRTPPPSQGK-amide substrate after 15 mins by autoradio...

Medchemcomm 6: 444-454 (2015)


BindingDB Entry DOI: 10.7270/Q2CJ8G9D
More data for this
Ligand-Target Pair