Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Cyclin-dependent kinase 2/G1/S-specific cyclin-E1' and Ligand = 'BDBM50443653'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cyclin-dependent kinase 2/G1/S-specific cyclin-E1 (Homo sapiens (Human))	BDBM50443653 (CHEMBL3093071) Show SMILES CC(C)(Nc1nnc(o1)-c1c[nH]c2ncccc12)c1ccccc1 Show InChI InChI=1S/C18H17N5O/c1-18(2,12-7-4-3-5-8-12)21-17-23-22-16(24-17)14-11-20-15-13(14)9-6-10-19-15/h3-11H,1-2H3,(H,19,20)(H,21,23)	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	7	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Inhibition of CDK2/cyclin E (unknown origin) using ULight peptide as substrate by HTRF assay				Bioorg Med Chem Lett 23: 6396-400 (2013) Article DOI: 10.1016/j.bmcl.2013.09.055 BindingDB Entry DOI: 10.7270/Q2P84DC0
					More data for this Ligand-Target Pair