Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Cyclin-dependent kinase 2/G1/S-specific cyclin-E1' and Ligand = 'BDBM5699'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cyclin-dependent kinase 2/G1/S-specific cyclin-E1 (Homo sapiens (Human))	BDBM5699 (2-amino-5-thio-substituted thiazole 67 | N-(5-{[(5...) Show SMILES CC(=O)Nc1ncc(SCc2nnsc2Cl)s1 Show InChI InChI=1S/C8H7ClN4OS3/c1-4(14)11-8-10-2-6(16-8)15-3-5-7(9)17-13-12-5/h2H,3H2,1H3,(H,10,11,14)	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Pharmaceutical Research Institute					Assay Description The enzyme was assayed with substrate in the presence of 25 uM ATP/[gamma-33P] ATP and test compound. Dose response curves were generated to determ...				J Med Chem 45: 3905-27 (2002) Article DOI: 10.1021/jm0201520 BindingDB Entry DOI: 10.7270/Q2GT5KC3
					More data for this Ligand-Target Pair