Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Cyclin-dependent kinase 2/G1/S-specific cyclin-E1' and Ligand = 'BDBM7656'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cyclin-dependent kinase 2/G1/S-specific cyclin-E1 (Homo sapiens (Human))	BDBM7656 (Imidazo[1,2-a]pyridine deriv. 1g | N-(3-chlorophen...) Show SMILES Clc1cccc(Nc2nccc(n2)-c2cnc3ccccn23)c1 Show InChI InChI=1S/C17H12ClN5/c18-12-4-3-5-13(10-12)21-17-19-8-7-14(22-17)15-11-20-16-6-1-2-9-23(15)16/h1-11H,(H,19,21,22)	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5	n/a	n/a	n/a	n/a	7.0	22
AstraZeneca					Assay Description The kinase activity was assayed using an in vitro scintillation proximity assay (SPA) for measuring incorporation of [gamma-33P] ATP into GST-Rb.				Bioorg Med Chem Lett 14: 2245-8 (2004) Article DOI: 10.1016/j.bmcl.2004.02.015 BindingDB Entry DOI: 10.7270/Q22805TT
					More data for this Ligand-Target Pair