Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Cyclin-dependent kinase 2' and Ligand = 'BDBM50263110'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cyclin-dependent kinase 2 (Homo sapiens (Human))	BDBM50263110 (2-(dimethylamino)-1-(4-(4-(4-(1-isopropyl-2-methyl...) Show SMILES CC(C)n1c(C)ncc1-c1ccnc(Nc2ccc(cc2)N2CCN(CC2)C(=O)CN(C)C)n1 Show InChI InChI=1S/C25H34N8O/c1-18(2)33-19(3)27-16-23(33)22-10-11-26-25(29-22)28-20-6-8-21(9-7-20)31-12-14-32(15-13-31)24(34)17-30(4)5/h6-11,16,18H,12-15,17H2,1-5H3,(H,26,28,29)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	16	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Pharmaceuticals Curated by ChEMBL					Assay Description Inhibition of CDK2/Cyclin E (unknown origin)				Bioorg Med Chem Lett 18: 4442-6 (2008) Article DOI: 10.1016/j.bmcl.2008.06.027 BindingDB Entry DOI: 10.7270/Q24749PG
					More data for this Ligand-Target Pair