Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Cyclin-dependent kinase 4/G1/S-specific cyclin-D1' and Ligand = 'BDBM6806'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cyclin-dependent kinase 4/G1/S-specific cyclin-D1 (Homo sapiens (Human))	BDBM6806 (6-(benzyloxy)-18-methyl-3,13,18-triazahexacyclo[14...) Show SMILES Cn1ccc2ccc3c4[nH]c5cc(OCc6ccccc6)ccc5c4c4C(=O)NC(=O)c4c3c12 Show InChI InChI=1S/C28H19N3O3/c1-31-12-11-16-7-9-19-22(26(16)31)24-23(27(32)30-28(24)33)21-18-10-8-17(13-20(18)29-25(19)21)34-14-15-5-3-2-4-6-15/h2-13,29H,14H2,1H3,(H,30,32,33)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	25	n/a	n/a	n/a	n/a	n/a	25
Lilly Research Laboratories					Assay Description In vitro CDK assay using purified enzyme, was incubated at room temperature with substrate, and test compounds in the presence of ATP/[gamma-33P]ATP....				Bioorg Med Chem Lett 13: 2261-7 (2003) Article DOI: 10.1016/s0960-894x(03)00461-x BindingDB Entry DOI: 10.7270/Q29W0CPW
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 4/G1/S-specific cyclin-D1 (Homo sapiens (Human))	BDBM6806 (6-(benzyloxy)-18-methyl-3,13,18-triazahexacyclo[14...) Show SMILES Cn1ccc2ccc3c4[nH]c5cc(OCc6ccccc6)ccc5c4c4C(=O)NC(=O)c4c3c12 Show InChI InChI=1S/C28H19N3O3/c1-31-12-11-16-7-9-19-22(26(16)31)24-23(27(32)30-28(24)33)21-18-10-8-17(13-20(18)29-25(19)21)34-14-15-5-3-2-4-6-15/h2-13,29H,14H2,1H3,(H,30,32,33)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	123	n/a	n/a	n/a	n/a	n/a	25
Lilly Research Laboratories					Assay Description In vitro CDK assay using purified enzyme, was incubated at room temperature with substrate, and test compounds in the presence of ATP/[gamma-33P]ATP....				Bioorg Med Chem Lett 13: 2261-7 (2003) Article DOI: 10.1016/s0960-894x(03)00461-x BindingDB Entry DOI: 10.7270/Q29W0CPW
					More data for this Ligand-Target Pair