Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Cyclin-dependent kinase 4' and Ligand = 'BDBM50273075'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cyclin-dependent kinase 4 (Homo sapiens (Human))	BDBM50273075 ((3,4-Dihydro-1H-pyrido[3,4-b]indol-2(9H)-yl)(3'-fl...) Show SMILES Fc1cccc(c1)-c1ccc(cc1)C(=O)N1CCc2c(C1)[nH]c1ccccc21 Show InChI InChI=1S/C24H19FN2O/c25-19-5-3-4-18(14-19)16-8-10-17(11-9-16)24(28)27-13-12-21-20-6-1-2-7-22(20)26-23(21)15-27/h1-11,14,26H,12-13,15H2	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.10E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Leicester Curated by ChEMBL					Assay Description Inhibition of human CDK4/GST-cyclin D1 expressed in Sf9 cells assessed as retinoblastoma GST-RB152 phosphorylation				Bioorg Med Chem 16: 7728-39 (2008) Article DOI: 10.1016/j.bmc.2008.07.002 BindingDB Entry DOI: 10.7270/Q2348K57
					More data for this Ligand-Target Pair