Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Cyclin-dependent kinase 5 activator 1' and Ligand = 'BDBM50304122'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cyclin-dependent kinase 5 activator 1 (Homo sapiens (Human))	BDBM50304122 ((Z)-5,7'-Dibromo-5'-nitro-1H,1'H-[2,3']biindolylid...) Show SMILES [O-][N+](=O)c1cc2C(C(=O)Nc2c(Br)c1)c1[nH]c2ccc(Br)cc2c1N=O Show InChI InChI=1S/C16H8Br2N4O4/c17-6-1-2-11-8(3-6)14(21-24)15(19-11)12-9-4-7(22(25)26)5-10(18)13(9)20-16(12)23/h1-5,12,19H,(H,20,23)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ de La Rochelle Curated by ChEMBL					Assay Description Inhibition of GST-fused CDK5/p25 expressed in Escherichia coli assessed as [gamma-33P]ATP incorporation after 10 mins by scintillation counting				Bioorg Med Chem 17: 6257-63 (2009) Article DOI: 10.1016/j.bmc.2009.07.051 BindingDB Entry DOI: 10.7270/Q2BR8S9W
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