Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Cyclin-dependent kinase 5 activator 1' and Ligand = 'BDBM50414907'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cyclin-dependent kinase 5 activator 1 (Homo sapiens (Human))	BDBM50414907 (CHEMBL584506) Show SMILES CCOC(=O)c1cc(-c2csc(n2)-c2ccncc2)c(=O)[nH]c1C1CC1 Show InChI InChI=1S/C19H17N3O3S/c1-2-25-19(24)14-9-13(17(23)22-16(14)11-3-4-11)15-10-26-18(21-15)12-5-7-20-8-6-12/h5-11H,2-4H2,1H3,(H,22,23)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	198	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc Curated by ChEMBL					Assay Description Inhibition of human CDK5/p25 assessed as histone h1 phosphorylation in presence of ATP				Bioorg Med Chem Lett 19: 6591-4 (2009) Article DOI: 10.1016/j.bmcl.2009.10.027 BindingDB Entry DOI: 10.7270/Q2K937KN
					More data for this Ligand-Target Pair