Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Cyclin-dependent kinase 5 activator 1 (Homo sapiens (Human)) | BDBM7453 (1-aza-9-oxafluorene deriv. 7b | 4-methoxy-3-phenyl...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | 2.17E+5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Martin-Luther University Halle-Wittenberg Curated by ChEMBL | Assay Description Inhibition of CDK5/p25 | Bioorg Med Chem Lett 22: 6914-8 (2012) Article DOI: 10.1016/j.bmcl.2012.09.006 BindingDB Entry DOI: 10.7270/Q2M61MC1 | |||||||||||
More data for this Ligand-Target Pair |