Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Cyclin-dependent kinase 5 activator 1 [99-307]' and Ligand = 'BDBM7368'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cyclin-dependent kinase 5 activator 1 [99-307] (Homo sapiens (Human))	BDBM7368 (4-{7-methyl-5H-pyrrolo[2,3-b]pyrazin-6-yl}phenyl N...) Show SMILES CN(C)S(=O)(=O)Oc1ccc(cc1)-c1[nH]c2nccnc2c1C Show InChI InChI=1S/C15H16N4O3S/c1-10-13(18-15-14(10)16-8-9-17-15)11-4-6-12(7-5-11)22-23(20,21)19(2)3/h4-9H,1-3H3,(H,17,18)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	900	n/a	n/a	n/a	n/a	n/a	30
Faculte de Medecine et de Pharmacie					Assay Description Kinase activities were assayed in buffers containing substrate, enzyme, and inhibitor at 30 °C in the presence of 15 uM ATP/ [gamma-32P] ATP. 32...				J Med Chem 46: 222-36 (2003) Article DOI: 10.1021/jm020319p BindingDB Entry DOI: 10.7270/Q2474820
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