Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Cyclin-dependent kinase 6/G1/S-specific cyclin-D1 [L188C]' and Ligand = 'BDBM472680'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cyclin-dependent kinase 6/G1/S-specific cyclin-D1 [L188C] (Homo sapiens (Human))	BDBM472680 (2-((5-(4-methylpiperazin-1- yl)pyridin-2-yl)amino)...) Show SMILES CN1CCN(CC1)c1ccc(Nc2ncc3C(=O)CC4N(CCNC4=O)c3n2)nc1 Show InChI InChI=1S/C20H24N8O2/c1-26-6-8-27(9-7-26)13-2-3-17(22-11-13)24-20-23-12-14-16(29)10-15-19(30)21-4-5-28(15)18(14)25-20/h2-3,11-12,15H,4-10H2,1H3,(H,21,30)(H,22,23,24,25)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	5.04E+4	n/a	n/a	n/a	n/a	n/a	n/a
GI Therapeutics, Inc. US Patent					Assay Description Selected compounds disclosed herein were tested in CDK4/cyclinD1, CDK2/CycA and CDK2/cyclinE kinase assays by Nanosyn (Santa Clara, Calif.) to determ...				US Patent US10829490 (2020) BindingDB Entry DOI: 10.7270/Q20V8GV8
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