Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Cyclin-dependent kinase 7 (Homo sapiens (Human)) | BDBM50358210 (CHEMBL1922123 | US8846696, (3R)-3-{9-Isopropyl-6-[...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | US Patent | n/a | n/a | 3.10E+3 | n/a | n/a | n/a | n/a | 7.4 | n/a |
Cyclacel Limited; Cancer Research Technology Limited US Patent | Assay Description The compounds from the examples below were investigated for their CDK2/cyclin E, CDK1/cyclin B, CDK4/cyclin D1 and CDK7/cyclin H, ERK-2, and PKA inhi... | US Patent US8846696 (2014) BindingDB Entry DOI: 10.7270/Q2Z31XCT | |||||||||||
More data for this Ligand-Target Pair |