Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Cyclin-dependent kinase 8' and Ligand = 'BDBM50585694'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cyclin-dependent kinase 8 (Homo sapiens (Human))	BDBM50585694 (CHEMBL4878072) Show SMILES CN1CCN(CC1)C(=O)c1ccc2cc(CCNc3ccnc4ccc(cc34)C#N)ccc2c1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	55	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Binding affinity to human CDK8 assessed as dissociation constant by KdELECT Discover assay				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c01951 BindingDB Entry DOI: 10.7270/Q2WD44G8
					More data for this Ligand-Target Pair