Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Cyclin-dependent kinase 9' and Ligand = 'BDBM106957'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cyclin-dependent kinase 9 (Homo sapiens (Human))	BDBM106957 (US8592581, 8) Show SMILES CC[C@H](Nc1nc(NC2CCC2)c2ncn(C(C)C)c2n1)[C@@H](C)O |r| Show InChI InChI=1S/C17H28N6O/c1-5-13(11(4)24)20-17-21-15(19-12-7-6-8-12)14-16(22-17)23(9-18-14)10(2)3/h9-13,24H,5-8H2,1-4H3,(H2,19,20,21,22)/t11-,13+/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	500	n/a	n/a	n/a	n/a	7.5	30
Cyclacel Limited; Cancer Research Technology Limited US Patent					Assay Description To evaluate the in-vitro kinase potency of the compounds, they were screened against CDK 2 and CDK9. Kinase assays were performed in 96-well plates u...				US Patent US8592581 (2013) BindingDB Entry DOI: 10.7270/Q25X27J9
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