Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Cyclin-dependent kinase 9' and Ligand = 'BDBM307880'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cyclin-dependent kinase 9 (Homo sapiens (Human))	BDBM307880 ( N-{5-chloro-4-[1-(3-fluorobenzyl)-1H-imidazo[4,5-...) Show SMILES Fc1cccc(Cn2cnc3ncc(cc23)-c2cc(NC(=O)C3CCCNC3)ncc2Cl)c1 Show InChI InChI=1S/C24H22ClFN6O/c25-20-12-28-22(31-24(33)16-4-2-6-27-10-16)9-19(20)17-8-21-23(29-11-17)30-14-32(21)13-15-3-1-5-18(26)7-15/h1,3,5,7-9,11-12,14,16,27H,2,4,6,10,13H2,(H,28,31,33)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	23	n/a	n/a	n/a	n/a	n/a	n/a
AbbVie Inc. US Patent					Assay Description CDK9 enzyme activities were measured using LANCE ULight TR-FRET kinase assay reagents (PerkinElmer, Waltham, Mass.). Compounds were directly added in...				US Patent US9650358 (2017) BindingDB Entry DOI: 10.7270/Q2057J0M
					More data for this Ligand-Target Pair