Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Cystathionine gamma-lyase' and Ligand = 'BDBM50280027'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cystathionine gamma-lyase (Homo sapiens (Human))	BDBM50280027 (CHEMBL4176749) Show SMILES Cn1cc(Cl)c(\C=N\NC(=S)SCC(=O)Nc2ccc(cc2)C(C)(C)C)n1 Show InChI InChI=1S/C18H22ClN5OS2/c1-18(2,3)12-5-7-13(8-6-12)21-16(25)11-27-17(26)22-20-9-15-14(19)10-24(4)23-15/h5-10H,11H2,1-4H3,(H,21,25)(H,22,26)/b20-9+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Illinois at Chicago Curated by ChEMBL					Assay Description Inhibition of cystathionine gamma-lyase (unknown origin) assessed as reduction in cysteine formation from CPM using L-cystathionine pre-incubated for...				ACS Med Chem Lett 8: 1241-1245 (2017) Article DOI: 10.1021/acsmedchemlett.7b00313 BindingDB Entry DOI: 10.7270/Q2N300GT
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