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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Cysteine protease' and Ligand = 'BDBM50263608'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Cysteine protease


(Trypanosoma brucei rhodesiense)		BDBM50263608
PNG
(CHEMBL4093144)
Show SMILES FC(F)(F)Oc1ccc(C[C@H](NC(=O)c2cnn(n2)C2CCC2)C(=O)NC2(CC2)C#N)cc1Cl |r|
Show InChI InChI=1S/C21H20ClF3N6O3/c22-14-8-12(4-5-17(14)34-21(23,24)25)9-15(19(33)29-20(11-26)6-7-20)28-18(32)16-10-27-31(30-16)13-2-1-3-13/h4-5,8,10,13,15H,1-3,6-7,9H2,(H,28,32)(H,29,33)/t15-/m0/s1
PDB
MMDB

UniProtKB/TrEMBL

B.MOAD
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars
Article
PubMed
 11n/an/an/an/an/an/an/an/a



Laboratorium für Organische Chemie , ETH Zurich , Vladimir-Prelog-Weg 3 , 8093 Zürich , Switzerland.

Curated by ChEMBL


Assay Description
Inhibition of Trypanosoma brucei rhodesiense rhodesain using Cbz-Phe-Arg-AMC as substrate by fluorimetric method

J Med Chem 61: 3370-3388 (2018)


Article DOI: 10.1021/acs.jmedchem.7b01870
BindingDB Entry DOI: 10.7270/Q2MC92GH
More data for this
Ligand-Target Pair