Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Cystic fibrosis transmembrane conductance regulator (Homo sapiens (Human)) | BDBM50237261 (CHEMBL4066115) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | n/a | n/a | n/a | n/a | 1.00E+3 | n/a | n/a | n/a | n/a |
University of California Curated by ChEMBL | Assay Description Activation of human CFTR expressed in FRT cells co-expressing YFP H148Q mutant assessed as increase in forskolin-stimulated iodide influx measured af... | J Med Chem 60: 2401-2410 (2017) Article DOI: 10.1021/acs.jmedchem.6b01759 BindingDB Entry DOI: 10.7270/Q2SN0C70 | |||||||||||
More data for this Ligand-Target Pair |