Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Cystic fibrosis transmembrane conductance regulator' and Ligand = 'BDBM50290126'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cystic fibrosis transmembrane conductance regulator (Homo sapiens (Human))	BDBM50290126 (CHEMBL3746133) Show SMILES CN(C)CCN1CCN(CC1)c1nc(nc2CCN(Cc3ccsc3)Cc12)-c1ccccn1 Show InChI InChI=1S/C25H33N7S/c1-29(2)10-11-30-12-14-32(15-13-30)25-21-18-31(17-20-7-16-33-19-20)9-6-22(21)27-24(28-25)23-5-3-4-8-26-23/h3-5,7-8,16,19H,6,9-15,17-18H2,1-2H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	200	n/a	n/a	n/a	n/a
Siena Biotech S.p.A. Curated by ChEMBL					Assay Description Corrector activity at human CFTR F508 deletion mutant expressed in FRT cells incubated for 25 mins with forskolin by YFP-based fluorescence analysis ...				J Med Chem 58: 9697-711 (2015) Article DOI: 10.1021/acs.jmedchem.5b00771 BindingDB Entry DOI: 10.7270/Q2VD72FT
					More data for this Ligand-Target Pair
Cystic fibrosis transmembrane conductance regulator (Homo sapiens (Human))	BDBM50290126 (CHEMBL3746133) Show SMILES CN(C)CCN1CCN(CC1)c1nc(nc2CCN(Cc3ccsc3)Cc12)-c1ccccn1 Show InChI InChI=1S/C25H33N7S/c1-29(2)10-11-30-12-14-32(15-13-30)25-21-18-31(17-20-7-16-33-19-20)9-6-22(21)27-24(28-25)23-5-3-4-8-26-23/h3-5,7-8,16,19H,6,9-15,17-18H2,1-2H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	200	n/a	n/a	n/a	n/a
University of Genoa Curated by ChEMBL					Assay Description Corrector activity at CFTR F508-del mutant (unknown origin) expressed in human CFBE41o cells harboring HS-YFP preincubated for 24 hrs followed by for...				Eur J Med Chem 144: 179-200 (2018) Article DOI: 10.1016/j.ejmech.2017.12.030 BindingDB Entry DOI: 10.7270/Q20K2C4K
					More data for this Ligand-Target Pair