Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Cystic fibrosis transmembrane conductance regulator' and Ligand = 'BDBM50353350'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cystic fibrosis transmembrane conductance regulator (Homo sapiens (Human))	BDBM50353350 (CHEMBL1831074) Show SMILES CCOC(=O)c1ccc2OC(c3ccc(C)o3)c3n(c(-c4ccccc4)c4c3n(C)c(=O)n(C)c4=O)-c2c1 Show InChI InChI=1S/C29H25N3O6/c1-5-36-28(34)18-12-14-20-19(15-18)32-23(17-9-7-6-8-10-17)22-24(30(3)29(35)31(4)27(22)33)25(32)26(38-20)21-13-11-16(2)37-21/h6-15,26H,5H2,1-4H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	80	n/a	n/a	n/a	n/a	n/a	n/a
University of California Curated by ChEMBL					Assay Description Inhibition of human wild-type CFTR expressed in FRT cells coexpressing YFP-H148Q assessed as inhibition of cAMP agonist-induced iodide influx after 4...				J Med Chem 54: 5468-77 (2011) Article DOI: 10.1021/jm200505e BindingDB Entry DOI: 10.7270/Q2280809
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