Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Cystic fibrosis transmembrane conductance regulator [1-507,509-1480]' and Ligand = 'BDBM160521'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cystic fibrosis transmembrane conductance regulator [1-507,509-1480] (Homo sapiens (Human))	BDBM160521 (US10280160, Example 13. | US9682969, 13) Show SMILES CN(C(=O)Cn1nc(-c2cccc(F)c2)c2ccc(O)cc2c1=O)c1ccc2nc(C)oc2c1 Show InChI InChI=1S/C25H19FN4O4/c1-14-27-21-9-6-17(11-22(21)34-14)29(2)23(32)13-30-25(33)20-12-18(31)7-8-19(20)24(28-30)15-4-3-5-16(26)10-15/h3-12,31H,13H2,1-2H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	<1.00E+4	n/a	n/a	n/a	n/a
Flatley Discovery Lab, LLC US Patent					Assay Description This protocol is designed to selectively screen small molecule compounds for F508del CFTR corrector activities in the YFP (yellow fluorescent protein...				US Patent US9682969 (2017) BindingDB Entry DOI: 10.7270/Q2SQ8XKT
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