Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Cystic fibrosis transmembrane conductance regulator [1-507,509-1480]' and Ligand = 'BDBM526513'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cystic fibrosis transmembrane conductance regulator [1-507,509-1480] (Homo sapiens (Human))	BDBM526513 (US11186566, Compound 52) Show SMILES C[C@@H]1CN(c2nc(ccc2C(=O)NS(=O)(=O)c2ccc(F)cc2)-n2ccc(OCC3(CC3)C(F)(F)F)n2)C(C)(C)C1 |r| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	<100	n/a	n/a	n/a	n/a
TBA					Assay Description The assay utilizes fluorescent voltage sensing dyes to measure changes in membrane potential using a fluorescent plate reader (e.g., FLIPR III, Molec...				Citation and Details BindingDB Entry DOI: 10.7270/Q22R3VVH
					More data for this Ligand-Target Pair