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Found 1 hit Enz. Inhib. hit(s) with Target = 'Cytochrome P450 11B1, mitochondrial' and Ligand = 'BDBM50395462'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Cytochrome P450 11B1, mitochondrial


(Homo sapiens (Human))		BDBM50395462
PNG
(CHEMBL2163647)
Show SMILES O=C1CCc2cc(cc3CCN1c23)C(c1cccc(c1)C#N)n1ccnc1
Show InChI InChI=1S/C22H18N4O/c23-13-15-2-1-3-16(10-15)21(25-9-7-24-14-25)19-11-17-4-5-20(27)26-8-6-18(12-19)22(17)26/h1-3,7,9-12,14,21H,4-6,8H2
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 144n/an/an/an/an/an/a



Saarland University and Helmholtz Institute for Pharmaceutical Research Saarland (HIPS)

Curated by ChEMBL


Assay Description
Inhibition of human CYP11B1 expressed in hamster V79 MZh cells using deoxycorticosterone substrate

J Med Chem 55: 6629-33 (2012)


Article DOI: 10.1021/jm3003872
BindingDB Entry DOI: 10.7270/Q2Q241CP
More data for this
Ligand-Target Pair