Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Cytochrome P450 1A2 (Homo sapiens (Human)) | BDBM50493818 (Oliceridine | TRV-130 | US11124523, Comparative Co...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase PC cid PC sid PDB UniChem | Article PubMed | n/a | n/a | >5.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of CYP1A2 (unknown origin) | Citation and Details Article DOI: 10.1016/j.ejmech.2021.113986 BindingDB Entry DOI: 10.7270/Q2TX3K84 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cytochrome P450 1A2 (Rattus norvegicus) | BDBM50493818 (Oliceridine | TRV-130 | US11124523, Comparative Co...) | Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | Purchase PC cid PC sid PDB UniChem | US Patent | n/a | n/a | >5.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description To test the inhibitory effects of the compounds of the present disclosure on different isoforms of human cytochrome P450 isoenzymes | Citation and Details BindingDB Entry DOI: 10.7270/Q2M90CTM | |||||||||||
More data for this Ligand-Target Pair |