Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Cytochrome P450 2C19 (Homo sapiens (Human)) | BDBM30705 (CHEMBL744 | MLS000069369 | RILUZOLE | SMR000058231...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | >2.50E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Modena and Reggio Emilia Curated by ChEMBL | Assay Description Inhibition of human CYP2C19 expressed in baculovirus infected insect cells using beetle D-luciferin as substrate preincubated for 30 mins followed by... | J Med Chem 62: 3989-4012 (2019) Article DOI: 10.1021/acs.jmedchem.8b02021 BindingDB Entry DOI: 10.7270/Q2HQ4399 | |||||||||||
More data for this Ligand-Target Pair |