Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Cytochrome P450 2C19 (Homo sapiens (Human)) | BDBM50208165 (CHEMBL3910904) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Patents | Article PubMed | n/a | n/a | >2.50E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Rhône-Poulenc Rorer Curated by ChEMBL | Assay Description Inhibition of CYP2C19 in human liver microsomes assessed as reduction in S-mephenytoin-4-hydroxylation at 1 to 25 uM by UPLC-MS/MS analysis | ACS Med Chem Lett 8: 118-123 (2017) Article DOI: 10.1021/acsmedchemlett.6b00438 BindingDB Entry DOI: 10.7270/Q2ZC84WF | |||||||||||
More data for this Ligand-Target Pair |