Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Cytochrome P450 family 11 subfamily B member 2' and Ligand = 'BDBM191282'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cytochrome P450 family 11 subfamily B member 2 (Cercopithecus sabaeus)	BDBM191282 (US9181272, 52) Show SMILES Cn1c(cc2ccccc12)-c1cncc(-c2cnc3N(CCCc3c2)C(N)=O)c1C#N Show InChI InChI=1S/C24H20N6O/c1-29-21-7-3-2-5-15(21)10-22(29)20-14-27-13-19(18(20)11-25)17-9-16-6-4-8-30(24(26)31)23(16)28-12-17/h2-3,5,7,9-10,12-14H,4,6,8H2,1H3,(H2,26,31)	MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	5.70	n/a	n/a	n/a	n/a	7.4	n/a
Boehringer Ingelheim International GmbH US Patent					Assay Description The aldosterone synthase inhibition assay employs cynomolgus adrenal gland mitochondria as the source of aldosterone synthase (CYP11B2). Mitochondr...				US Patent US9181272 (2015) BindingDB Entry DOI: 10.7270/Q2VX0F93
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