Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Cytoplasmic tyrosine-protein kinase BMX' and Ligand = 'BDBM50236086'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cytoplasmic tyrosine-protein kinase BMX (Homo sapiens (Human))	BDBM50236086 (CHEMBL4068296) Show SMILES CNc1nc(Nc2ccc(C)c(NC(=O)C=C)c2)ncc1C(=O)Nc1cc(NC(=O)c2ccc3OCOc3c2)ccc1C Show InChI InChI=1S/C31H29N7O5/c1-5-27(39)36-23-14-21(10-7-17(23)2)35-31-33-15-22(28(32-4)38-31)30(41)37-24-13-20(9-6-18(24)3)34-29(40)19-8-11-25-26(12-19)43-16-42-25/h5-15H,1,16H2,2-4H3,(H,34,40)(H,36,39)(H,37,41)(H2,32,33,35,38)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.56E+3	n/a	n/a	n/a	n/a	n/a	n/a
High Magnetic Field Laboratory Curated by ChEMBL					Assay Description Inhibitory activity against radioligand [3H]nisoxetine binding at the norepinephrine transporter				J Med Chem 60: 1793-1816 (2017) Article DOI: 10.1021/acs.jmedchem.6b01413 BindingDB Entry DOI: 10.7270/Q2GH9M74
					More data for this Ligand-Target Pair