BindingDB PrimarySearch

Found 12 hits Enz. Inhib. hit(s) with Target = 'D(1A) dopamine receptor' and Ligand = 'BDBM84637'
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
D(1A) dopamine receptor (Homo sapiens (Human))	BDBM84637 (CAS_85760-74-3 \| CHEMBL240773 \| NSC_54562 \| QUINPI...) Show SMILES CCCN1CCC[C@@H]2Cc3[nH]ncc3C[C@@H]12 \|r\| Show InChI	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	63	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Friedrich Alexander University Curated by ChEMBL					Assay Description Binding affinity (high) towards human dopamine receptor 2 long against radioligand [3H]spiperone, expressed in Chinese hamster ovary cells				J Med Chem 48: 5771-9 (2005) Article DOI: 10.1021/jm0503805 BindingDB Entry DOI: 10.7270/Q2KW5GT9
Friedrich Alexander University Curated by ChEMBL					More data for this Ligand-Target Pair
D(1A) dopamine receptor (RAT)	BDBM84637 (CAS_85760-74-3 \| CHEMBL240773 \| NSC_54562 \| QUINPI...) Show SMILES CCCN1CCC[C@@H]2Cc3[nH]ncc3C[C@@H]12 \|r\| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of North Carolina Curated by PDSP K_i Database									J Pharmacol Exp Ther 301: 1166-78 (2002) Article DOI: 10.1124/jpet.301.3.1166 BindingDB Entry DOI: 10.7270/Q2V69H4V
University of North Carolina Curated by PDSP K_i Database					More data for this Ligand-Target Pair
D(1A) dopamine receptor (BOVINE)	BDBM84637 (CAS_85760-74-3 \| CHEMBL240773 \| NSC_54562 \| QUINPI...) Show SMILES CCCN1CCC[C@@H]2Cc3[nH]ncc3C[C@@H]12 \|r\| Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Nebraska Curated by PDSP K_i Database									J Pharmacol Exp Ther 253: 214-20 (1990) BindingDB Entry DOI: 10.7270/Q2PN9447
University of Nebraska Curated by PDSP K_i Database					More data for this Ligand-Target Pair
D(1A) dopamine receptor (Homo sapiens (Human))	BDBM84637 (CAS_85760-74-3 \| CHEMBL240773 \| NSC_54562 \| QUINPI...) Show SMILES CCCN1CCC[C@@H]2Cc3[nH]ncc3C[C@@H]12 \|r\| Show InChI	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
SRI International Curated by PDSP K_i Database									NIDA Res Monogr 178: 440-66 (1998) BindingDB Entry DOI: 10.7270/Q23J3BH2
SRI International Curated by PDSP K_i Database					More data for this Ligand-Target Pair
D(1A) dopamine receptor (Homo sapiens (Human))	BDBM84637 (CAS_85760-74-3 \| CHEMBL240773 \| NSC_54562 \| QUINPI...) Show SMILES CCCN1CCC[C@@H]2Cc3[nH]ncc3C[C@@H]12 \|r\| Show InChI	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Institut de Recherches Servier Curated by PDSP K_i Database									J Pharmacol Exp Ther 303: 791-804 (2002) Article DOI: 10.1124/jpet.102.039867 BindingDB Entry DOI: 10.7270/Q2MG7N2F
					More data for this Ligand-Target Pair
D(1A) dopamine receptor (Homo sapiens (Human))	BDBM84637 (CAS_85760-74-3 \| CHEMBL240773 \| NSC_54562 \| QUINPI...) Show SMILES CCCN1CCC[C@@H]2Cc3[nH]ncc3C[C@@H]12 \|r\| Show InChI	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Innsbruck Curated by ChEMBL					Assay Description Displacement of [3H]SCH-23390 from human dopamine D1 receptor expressed in LHD1 cells				J Med Chem 55: 10302-6 (2012) Article DOI: 10.1021/jm301258w BindingDB Entry DOI: 10.7270/Q24X58ZX
University of Innsbruck Curated by ChEMBL					More data for this Ligand-Target Pair
D(1A) dopamine receptor (BOVINE)	BDBM84637 (CAS_85760-74-3 \| CHEMBL240773 \| NSC_54562 \| QUINPI...) Show SMILES CCCN1CCC[C@@H]2Cc3[nH]ncc3C[C@@H]12 \|r\| Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	>2.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Friedrich-Alexander University Curated by ChEMBL					Assay Description Inhibition constant against [3H]-SCH-23,390 binding to Dopamine receptor D1 in bovine striatal membranes				J Med Chem 48: 2493-508 (2005) Article DOI: 10.1021/jm049269+ BindingDB Entry DOI: 10.7270/Q2TT4QGT
Friedrich-Alexander University Curated by ChEMBL					More data for this Ligand-Target Pair
D(1A) dopamine receptor (BOVINE)	BDBM84637 (CAS_85760-74-3 \| CHEMBL240773 \| NSC_54562 \| QUINPI...) Show SMILES CCCN1CCC[C@@H]2Cc3[nH]ncc3C[C@@H]12 \|r\| Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	>2.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Friedrich Alexander University Curated by ChEMBL					Assay Description Binding affinity (low) towards bovine dopamine receptor 1 by using [3H]-SCH- 23390 (0.3 nM) as radioligand				J Med Chem 48: 5771-9 (2005) Article DOI: 10.1021/jm0503805 BindingDB Entry DOI: 10.7270/Q2KW5GT9
Friedrich Alexander University Curated by ChEMBL					More data for this Ligand-Target Pair
D(1A) dopamine receptor (Sus scrofa)	BDBM84637 (CAS_85760-74-3 \| CHEMBL240773 \| NSC_54562 \| QUINPI...) Show SMILES CCCN1CCC[C@@H]2Cc3[nH]ncc3C[C@@H]12 \|r\| Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	7.20E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Friedrich Alexander University Curated by ChEMBL					Assay Description Displacement of [3H]SCH23390 from dopamine D1 receptor in pig striatal membranes				J Med Chem 52: 6860-70 (2009) Article DOI: 10.1021/jm901120h BindingDB Entry DOI: 10.7270/Q2P84BZS
Friedrich Alexander University Curated by ChEMBL					More data for this Ligand-Target Pair
D(1A) dopamine receptor (Sus scrofa)	BDBM84637 (CAS_85760-74-3 \| CHEMBL240773 \| NSC_54562 \| QUINPI...) Show SMILES CCCN1CCC[C@@H]2Cc3[nH]ncc3C[C@@H]12 \|r\| Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	8.70E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Friedrich Alexander University Curated by ChEMBL					Assay Description Displacement of [3H]SCH23390 from dopamine D1 receptor in porcine striatal membranes				J Med Chem 56: 5130-41 (2013) Article DOI: 10.1021/jm400520c BindingDB Entry DOI: 10.7270/Q2PR7XDM
Friedrich Alexander University Curated by ChEMBL					More data for this Ligand-Target Pair
D(1A) dopamine receptor (Homo sapiens (Human))	BDBM84637 (CAS_85760-74-3 \| CHEMBL240773 \| NSC_54562 \| QUINPI...) Show SMILES CCCN1CCC[C@@H]2Cc3[nH]ncc3C[C@@H]12 \|r\| Show InChI	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	5.25E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Texas at Austin Curated by ChEMBL					Assay Description Affinity towards Dopamine receptor D1				J Med Chem 41: 4385-99 (1998) Article DOI: 10.1021/jm9800292 BindingDB Entry DOI: 10.7270/Q2R21227
University of Texas at Austin Curated by ChEMBL					More data for this Ligand-Target Pair
D(1A) dopamine receptor (RAT)	BDBM84637 (CAS_85760-74-3 \| CHEMBL240773 \| NSC_54562 \| QUINPI...) Show SMILES CCCN1CCC[C@@H]2Cc3[nH]ncc3C[C@@H]12 \|r\| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	PubMed	n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Purdue University Curated by ChEMBL					Assay Description Displacement of [3H]- #NAME? from binding Dopamine receptor D1 in rat striatum				J Med Chem 33: 1756-64 (1990) BindingDB Entry DOI: 10.7270/Q23X877X
Purdue University Curated by ChEMBL					More data for this Ligand-Target Pair